The nuclear membrane proteome: extending the envelope.

Explorer The nuclear membrane proteome : extending the envelope

Arabidopsis leaf plasma membrane proteome using a gel free method: Focus on receptor–like kinases

The hydrophobic proteins of plant plasma membrane still remain largely unknown.  For example in the Arabidopsis genome, receptor-like kinases (RLKs) are plasma membrane proteins, functioning as the primary receptors in the signaling of stress conditions, hormones and the presence of pathogens form a diverse family of over 610 genes. A limited number of these proteins have appeard in pr...

The nuclear envelope proteome differs notably between tissues

One hypothesis to explain how mutations in the same nuclear envelope proteins yield pathologies focused in distinct tissues is that as yet unidentified tissue-specific partners mediate the disease pathologies. The nuclear envelope proteome was recently determined from leukocytes and muscle. Here the same methodology is applied to liver and a direct comparison of the liver, muscle and leukocyte ...

The Leukocyte Nuclear Envelope Proteome Varies with Cell Activation and Contains Novel Transmembrane Proteins That Affect Genome Architecture*□S

Citation for published version: Korfali, N, Wilkie, GS, Swanson, SK, Srsen, V, Batrakou, DG, Fairley, EAL, Malik, P, Zuleger, N, Goncharevich, A, de Las Heras, J, Kelly, DA, Kerr, ARW, Florens, L & Schirmer, EC 2010, 'The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture' Molecular and Cellular Proteomics, v...

Analysis of membrane proteins localizing to the inner nuclear envelope in living cells

Understanding the protein composition of the inner nuclear membrane (INM) is fundamental to elucidating its role in normal nuclear function and in disease; however, few tools exist to examine the INM in living cells, and the INM-specific proteome remains poorly characterized. Here, we adapted split green fluorescent protein (split-GFP) to systematically localize known and predicted integral mem...